A publication in TrAC Trends in Analytical Chemistry has covered the recent advances in microfluidic liquid chromatography.
A publication in TrAC Trends in Analytical Chemistry has covered the recent advances in microfluidic liquid chromatography (from January 2013 through April 2015). Featuring a comprehensive guide to the latest technological improvements in both device robustness, instrument integration, efficiency, and portability, the review covers low-cost separation techniques in the form of monolithic stationary phases in polymeric chips and postulates on the development of disposable, oneâtime use chromatographic columns. The possibilities of 3D printing and the impact this technology could have in terms of substrate fabrication or the manufacturing of a fully integrated instrument–column hybrid are also discussed.
For more information please see J.P. Grinias and R.T. Kennedy, TrAC, Trends Anal. Chem. 81, 110–117 (2016) doi:10.1016/j.trac.2015.08.002
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.