From the Publisher: Offering Solutions to Today's Problems
The Application Notebook
It is no secret that these are tumultuous times we live in. With the economic slowdown, increased dangers abroad, and the recent string of scares involving toxins in everyday foods, there is no shortage of things to worry about in today's world. At LCGC, we've always felt that our Application Notebook is a reflection of not just the recent developments in chromatography and the field of separation science in general, but the world as a whole.
It is no secret that these are tumultuous times we live in. With the economic slowdown, increased dangers abroad, and the recent string of scares involving toxins in everyday foods, there is no shortage of things to worry about in today's world. At LCGC, we've always felt that our Application Notebook is a reflection of not just the recent developments in chromatography and the field of separation science in general, but the world as a whole.
Michael J. Tessalone
In these pages, you'll find application notes on the detection of chemical warfare agents, the analysis of melamine in milk supplies, reducing solvent usage for savings in the lab, and more, all reflecting issues and crises that have come to the forefront in our society as a whole. It has often been said that there is no point in identifying a problem without offering a constructive solution as well, and in The Application Notebook, you will find an entire issue dedicated to solving problems, as we follow LCGC's motto of offering "Solutions for separation scientists."
As usual, myself and our staff will be out in the marketplace as much as possible in the coming months, as the summer and fall have a busy schedule of conferences and symposia slated, so please feel free to give us your feedback on this or any of our other issues either in person or via the contact information on the masthead. This summer in particular will give readers and advertisers the chance to find all of LCGC's staff in one place at our second annual PharmSep Symposium, to be held in Philadelphia, Pennsylvania, September 21–22, so we hope you will attend. For more information on this event, just visit: www.lcgcevent.com.
In the meantime, we hope you enjoy this issue and the market barometer it provides, and we look forward to seeing as many of our readers and advertisers as possible over the coming months.
Michael J. Tessalone
Science Group Publisher
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
