The Pharma QC Column: OROSIL C18
The Application Notebook
The QC for the pharmaceutical industry is based on methods developed on a variety of columns. At Orochem, we have attempted to address method development utilizing unique chemistries such as the OROSIL C18 to analyze a wide range of acidic, basic, and neutral compounds. Data is presented on a few representative compounds and unique separation criteria with their associated chromatograms.
The QC for the pharmaceutical industry is based on methods developed on a variety of columns. At Orochem, we have attempted to address method development utilizing unique chemistries such as the OROSIL C18 to analyze a wide range of acidic, basic, and neutral compounds. Data is presented on a few representative compounds and unique separation criteria with their associated chromatograms.
Figure 1
Conclusion
We have successfully developed methods for more than 25 analytes with the Orosil C18 column. The OROSIL C18 chemistry provides a unique platform for the analytes currently targeted by the pharma industry towards major diseased states.
Orochem Technologies Inc,
Eisenhower Ln South, Lombard, IL 60148
Tel: 630-916-0225
Pick Your Poison: Isolation of Paclitaxel (Oct 2024)
October 4th 2024The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.
