Gathering information about the chemical and physical properties of target analytes is an essential step to effective solid-phase extraction (SPE) method development.
Gathering information about the chemical and physical properties of target analytes is an essential step to effective solid-phase extraction (SPE) method development. Log P, log D and pKa are key analyte characteristics that can have a significant impact on the rapid success of reversed-phase SPE method development. This article explores the value of these chemical properties and demonstrates their importance in efficient reversed-phase SPE method development and optimization.