Musings from the Little Black Book of GC
Incognito allows us to see into his little black book of GC facts.
I have a little black book that I have kept since starting my laboratory career (and is, therefore, not so little any longer), which contains useful facts or little known information that I have picked up over the years. Recently, I have been involved in several discussions that suggest some of this information has fallen from common knowledge or has been forgotten. One colleague suggested I publish a sample of tips and tricks from my notebook and invite replies to test this theory. So, this month I present part 1 of a smorgasbord of items that have surprised, helped or been truly revelatory to me during my GC career - I hope you also find them useful, informative or both. I would like to invite you all to reply with comments, corrections or your own ‘killer facts’ and contribute to the ‘Big Book of GC Facts’, which we may collectively publish for the benefit of all GC practitioners ([email protected]).
Next Generation Peak Fitting for Separations
December 11th 2024Separation scientists frequently encounter critical pairs that are difficult to separate in a complex mixture. To save time and expensive solvents, an effective alternative to conventional screening protocols or mathematical peak width reduction is called iterative curve fitting.
Identifying and Rectifying the Misuse of Retention Indices in GC
December 10th 2024LCGC International spoke to Phil Marriott and Humberto Bizzo about a recent paper they published identifying the incorrect use of retention indices in gas chromatography and how this problem can be rectified in practice.
