Flash chromatography is a type of preparative liquid chromatography commonly used in the separation of organic compounds.
Flash chromatography is a type of preparative liquid chromatography commonly used in the separation of organic compounds. It uses a plastic column filled with some form of solid support, usually silica gel, with the sample to be separated placed on top of this support. The rest of the column is filled with an isocratic or gradient solvent that with the help of pressure, enables the sample to run through the column and become separated.
PLS-DA With Univariate Filtration Refines Discovery of Untargeted Metabolomics Data Using LC–MS
May 23rd 2024As opposed to targeted metabolomics which looks only at a predetermined set of metabolites or their pathways, an untargeted approach was preferred by this research team because of its unbiased yet still comprehensive nature.