Synthetic cannabinoids, commonly found in ?herbal incense? brands were recently declared controlled substances by the US Drug Enforcement Agency. To assist the drug testing industry in detecting these substances, Agilent Technologies has produced a GC?MS compendium.
Synthetic cannabinoids, commonly found in ‘herbal incense’ brands were recently declared controlled substances by the US Drug Enforcement Agency. To assist the drug testing industry in detecting these substances, Agilent Technologies has produced a GC–MS compendium.
“These compounds had not been controlled until November of 2010, when health concerns prompted the DEA to evoke an emergency ban,” said Tom Gluodenis, the company’s forensic and toxicology business manager. “They present a number of analytical challenges. Formulations are rapidly evolving. When one is banned, it can quickly be replaced by a new one. They’re often sold in botanical matrixes as ‘herbal incense’ and other products, which presents additional challenges. We published this compendium to help labs get a handle on this dynamic situation.”
The compendium contains detailed procedures for sample preparation and GC–MS methods, plus a searchable mass-spectral library to test for 35 synthetic cannabinoids and their derivatives. The method and library were developed in collaboration with the Criminalistics Division of NMS Labs, an independent forensic laboratory certified by the American Board of Forensic Toxicology and the American Society of Crime Laboratory Directors.
To order a copy visit www.agilent.com/chem/cannabinoidcd
This story originally appeared in The Column. Click here to view that issue.
Investigating 3D-Printable Stationary Phases in Liquid Chromatography
May 7th 20253D printing technology has potential in chromatography, but a major challenge is developing materials with both high porosity and robust mechanical properties. Recently, scientists compared the separation performances of eight different 3D printable stationary phases.
Detecting Hyper-Fast Chromatographic Peaks Using Ion Mobility Spectrometry
May 6th 2025Ion mobility spectrometers can detect trace compounds quickly, though they can face various issues with detecting certain peaks. University of Hannover scientists created a new system for resolving hyper-fast gas chromatography (GC) peaks.
University of Oklahoma and UC Davis Researchers Probe Lipidomic Profiles with RP-LC–HRMS/MS
May 6th 2025A joint study between the University of Oklahoma Health Sciences Center (Oklahoma City, Oklahoma) and the UC Davis West Coast Metabolomics Center (Davis, California) identified differentially regulated lipids in type 2 diabetes (T2D) and obesity through the application of reversed-phase liquid chromatography-accurate mass tandem mass spectrometry (RP-LC-accurate MS/MS).