Digital Update
The latest digital products
New Chromatography e-learning modules
CHROMacademy is a chromatography e-learning programme that provides continuing profesional development for chromatographers to make them more effective in the work place. There are over 3000 pages of e-learning on HPLC, GC, MS and Sample Preperation techniques to improve practical knowledge for the absolute novice (What is Chromatography?) to the expert who needs a refresher in a particular topic (Advanced Topics in LC-MS Spectral Interpretation, for example). The site can be also used for induction training or programmed learning activites and there are tutorials and assessments built into all learning modules to check progress. The first official webinar: Essential Guide 1: Split /Splitless Injection for Capillary GC attracted 568 visitors. The recorded session is available via the CHROMmunity at http://chrommunity.chromacademy.com (under the WEBCASTS Tab). Other Webcasts include Essential Guide 2: Mobile Phase Optimization Strategies for Reversed Phase HPLC; Essential Guide 3: Understanding and Optimizing Detectors for Capillary GC; and Essential Guide 4: Mobile Phase Optimization Strategies for Reversed Phase HPLC.
On-line community for SDMS users
Waters has launched an on-line community featuring resources for users of the company's Empower software and NuGenesis scientific data management system (SDMS) as well as access to experts and shared user experiences. The site provides easy access to the latest information about software, targeted support materials and exclusive content only available to the community, according to the company, To date some of the most popular discussion topics among members include data sharing between colleagues around the world, Window 7 support for Empower and SDMS and validation requirements for chromatography data systems.
Biomarker discovery platform
Shimadzu Scientific Instruments has partnered with Ceres Nanosciences and Nonlinear Dynamics to release the Nanotrap Biomarker Discovery Platform, which the company claims gives researchers the ability to enrich, preserve and screen low-level biomarkers directly from complex biological samples. Nanotraps are core shell hydrogel particles with porous interiors and size exclusion shells. Progenesis MALDI, the software component of the platform, is reported to generate high-quality proteomics data to define biomarkers. It uses the Progenesis approach and technology to improve the reliability and reproducibility of results which, according to the company, adds speed, objectivity and statistics to biomarker discovery.
Petrochemical analysis software
DataApex has announced enhancements for Clarity Chromatography Software available in the updated version 2.8. According to the company, the added optional extension for natural gas analysis (NGA) calculations greatly enhances use in the petrochemical industry. The NGA extension performs the compression factor, mean molecular weight, density, Wobbe index and other calculations using different norms. The new Launch Manager utility allows the system to start with predefined profiles with different configurations and user preferences to facilitate switching instrument configurations. The OQ Validation Wizard guides the user through the operational qualification of the software that can now validate digital detectors.
Chemical and sensory database
Alpha MOS has developed a new database for aroma and chemical characterization by gas chromatography analysis. The AroChemBase library uses the Kovats Index as a reference method and is reported to include 2900 compounds of which 1400 have sensory attributes, with chemical information (Name, formula, CAS number, molecular weight, Retention Index) available for several columns. According to the company, when used with a two-column GC-based electronic nose or GC system, it allows a dual-column identification and ranking. The database can be enriched with user data and it is also possible to extract tailored sub-libraries.
Informatics system
Bio-Rad has released a fully integrated software and database package to provide multiple tools, including database building and management, search, analysis, structure drawing and reporting within a single user interface. According to the company, the KnowItAll Informatics System 8.2 includes a series of new report templates for more efficient output and improved design and a function to preview chromatograms and spectra to be used for searching, interpretation or database creation before the file is actually opened. The informatics system is reported to offer a fully integrated environment with flexible and expandable software and database solutions for chromatography, MS, cheminformatics; chemometrics, metabolomics and more.
Lab automation system
Labtronics has announced the release of Nexxis iLAB 5.0, a total lab automation system. This system integrates ELN, SDMS and instrument integration into a single package that is ready to go out of the box, according to the company. The company claims that it enhances the value of an existing LIMS by providing extra functionality. It controls the analyst step-by-step to prevent mistakes, enforces training and prevents an analyst from doing work if training has expired, according to the company. Expiration dates on chemicals and the calibration on instruments are current and enforced.
Evaporators and concentration systems website
Genevac has announced an online resource that the company claims brings together the latest technological innovations, applications advances and links to references that detail the current scope of evaporative sample preparation techniques used in clinical and diagnostic testing. Visitors to the website can learn how the company's evaporators and concentration systems are used by clinical biochemists for a number of testing methods, including vitamin D analysis, vitamin K analysis, drugs of abuse testing and neonatal screening. To enable scientists to understand the detail of the various evaporative and concentration techniques used in these applications, further background information can be found in the technology section.
Send any digital developments in chromatography to Doug Kitson at dkitson@advanstar.com
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Katelynn Perrault Uptmor Receives the 2025 LCGC Emerging Leader in Chromatography Award
Published: November 13th 2024 | Updated: November 13th 2024November 13, 2024 – LCGC International magazine has named Katelynn A. Perrault Uptmor, Assistant Professor of Chemistry at the College of William & Mary, the recipient of the 2025 Emerging Leader in Chromatography Award. This accolade, which highlights exceptional achievements by early-career scientists, celebrates Perrault Uptmor’s pioneering work in chromatography, particularly in the fields of forensic science, odor analysis, and complex volatile organic compounds (VOCs) research.
