Special Issues
Formaldehyde is widely used in manufacturing of building materials, cars, plywood, polymers, glues, and adhesives. It is also commonly used in household items as a preservative and disinfectant. Due to high toxicity and suspected carcinogenicity, products are tested to determine free formaldehyde content and ensure the safety of personal care products and other items. Free formaldehyde testing is also important to monitor production of resins and other polymers and to ensure the quality of final materials.
HPLC method with post-column derivatization allows for quantifying free formaldehyde in a wide range of products and materials, from shampoos to emulsion polymers and phenolic resins. The method is simple, selective, and very sensitive. Potential interferences are either separated from formaldehyde on HPLC column or don't react with post-column reagent and so are not interfering with the detection.
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A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.
GPCRs – The Biological Traffic Modulator: Chromatographic Analysis of Peptides in the GI Tract
January 20th 2025The G protein-coupled receptors (GPCR) are found throughout the entire body and have shown significance in the development of new therapeutic treatments. Isolation of seven classic GRPC peptides initiating in the GI tract highlights the benefits of using the polymer-based PRP-3, a reversed-phase resin. The covalent bonds found in the PRP-3 exhibit advantageous interactions between the biological π bonds found in the peptides and the available aromatic benzyl rings of the resin.