Accelerating Proteomic Biomarker Validation
The optimum in proteomics research today is in validating the performance of promising biomarkers across large biological sample sets. Many new strategies have been developed in recent years to improve and accelerate targeted MS verification assays.
The optimum in proteomics research today is in validating the performance of promising biomarkers across large biological sample sets. Many new strategies have been developed in recent years to improve and accelerate targeted MS verification assays. One of the more promising strategies involves combining column-switching techniques for multiplexed nano‑LC with MS instrumentation and software that performs time-scheduled multiple reaction monitoring (MRM). In this article we will demonstrate an effective workflow that incorporates advanced LC and MS techniques to significantly improve throughput and accelerate biomarker verification.
Green Chemistry: What is it (and What Is It Not)? And How Does It Apply to Gas Chromatography?
October 31st 2024Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?
HILIC Peptide Retention Times Predicted Using New Approach
October 29th 2024Manitoba Centre for Proteomics and Systems Biology scientists produced a new means of predicting peptide retention times for hydrophilic interaction liquid chromatography (HILIC) at acidic pH in formic-acid based eluents.
A Review of the Latest Separation Science Research in PFAS Analysis
October 17th 2024This review aims to provide a summary of the most current analytical techniques and their applications in per- and polyfluoroalkyl substances (PFAS) research, contributing to the ongoing efforts to monitor and mitigate PFAS contamination.
