A New Analytical Perspective: Techniques To Characterize AAV Quality Attributes
Webinar Date/Time: Thursday, December 7, 2023 at 9am EST | 2pm GMT | 3pm CET Thursday, December 7, 2023 at 1pm EST | 12pm CST | 10am PST
This webcast focuses on how to improve the accuracy of viral particle analysis using the combination of SEC-MALS and IEX. Significant ongoing efforts to address manufacturing and research methods for viral particle analysis are of major interest within the gene and cell therapy industries. Discover advanced solutions to characterize quality attributes of viral particles using newly developed chromatographic methods coupled with multi-angle light scattering detection. New data analysis software features will be demonstrated that allow for quick and easy calculations specific to viral particles.
Register Free: https://www.chromatographyonline.com/lcgc_w/AAV
Event Overview:
This webinar will present multiple novel analytical methods developed for viral particle drug delivery platforms. The presentation will highlight newly developed HPLC methods to improve the separation and analysis of viral particles such as AAVs with a focus on ion-exchange and size-exclusion chromatography. Additionally, we will discuss instrumentation and analysis for viral particles, highlighting the utility of multi-angle light scattering (MALS) detection. This webcast targets those looking for complete workflows for characterizing drug delivery vehicles relevant to gene and cell therapy, covering the various methods by which chromatography, instrumentation, and software provide a complementary approach towards comprehensive viral particle analysis.
Key Learning Objectives:
- Highlight novel analytical methods for improved chromatography of viral particle analysis
- Discuss advantages of multi-angle light scattering detection for viral particles
- Learn about new software features for assessment of viral particle quality attributes
Who Should Attend:
- Laboratory scientists and managers seeking analytical technology to improve viral particle analysis workflows
- Analysts developing therapeutic products for gene and cell therapy
- Analysts seeking new tools for simplified AAV manufacturing solutions
Speaker:
Farihah Haque
Regional Product Specialist
Tosoh Bioscience
Farihah Haque completed her PhD in polymer chemistry at Tulane University where she studied cyclic polymers. Thereafter, she pursued a post-doctoral fellowship at the University of Minnesota studying sustainable elastomers in the NSF Center for Sustainable Polymers. She joined Tosoh Bioscience in 2021, as an Applications Scientist developing analytical methods for polymer characterization. Now, as a regional product specialist, she helps customers analyze biological macromolecules for gene therapy, implementing advanced chromatography techniques to effectively characterize these materials.
Register Free: https://www.chromatographyonline.com/lcgc_w/AAV
USP CEO Discusses Quality and Partnership in Pharma
December 11th 2024Ronald Piervincenzi, chief executive officer of the United States Pharmacoepia, focused on how collaboration and component quality can improve worldwide pharmaceutical production standards during a lecture at the Eastern Analytical Symposium (EAS) last month.
Overcoming Common Challenges to Determine Residual Impurities Using IC in APIs with Limited Water
December 10th 2024Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.
The Benefits of DBS-GC–MS/MS in Barbiturate Detection
December 5th 2024Three analytical and two pre-treatment methods—gas chromatography–mass spectrometry (GC–MS), gas chromatography–tandem mass spectrometry (GC–MS/MS), and liquid chromatography–tandem mass spectrometry (LC–MS/MS) plus liquid-liquid extraction (LLE) and dried blood spot (DBS) —were compared for the quantitation and characterization of barbiturates.
