All News
LC workshops – something for the spring
March 1st 2006Two LC workshops will be held between 8?10 May at The Rubens at The Palace Hotel, London, UK. The courses are aimed at improving method development and providing solutions to common problems that occur with LC methods. The courses are brought by LC Resources and LCGC Europe, and sponsored by Hichrom.
1200 series LC system launched
February 1st 2006Agilent Technologies has introduced the 1200 Series liquid chromatography system as a successor to its 1100 Series LC. Liquid chromatography represents a $2 billion market and is one of the largest sources of revenue for Agilent's life science and chemical analysis business. Since introducing the 1100 Series instrument in 1995, Agilent has sold more than 400000 modules or 60000 LC systems. To ease the transition to the 1200 Series, the company has made the system reverse-compatible with the 1100 so that customers can combine new and existing modules and continue using existing methods without costly new method development, revalidation or retraining of operators. With more than 60 instrument modules, the system can be configured for all major LC applications, including a rapid-resolution format, preparative scale, standard, narrow, capillary, nanoflow and the company's chip-based liquid chromatography.
Miniaturized Approaches to Conventional Liquid–Liquid Extraction
February 1st 2006Liquid-liquid extraction (LLE) is among the most widely used sample preparation methods. In this month's installment of "Sample Prep Perspectives," Ron Majors discusses newer LLE approaches that offer significant advantages over classical methods. The miniaturization of LLE has resulted in solvent and time savings, improved automation possibilities, and faster sample preparation. The techniques of single-drop microextraction, extraction in levitated droplets, flow injection-, membrane-based-, and solid-supported extractions are reviewed. Often, these techniques use the same immiscible solvent pairs of conventional LLE.
Automation of the Chromatographic Analytical Method Validation Process
February 1st 2006This article describes a software solution for automating the chromatographic method validation process starting from experimental planning, data acquisition and processing, through final report generation in a seamless manner. All experimental planning and calculations are accomplished within the chromatography data software and, thus, are structurally validated, secure, and audit trailed. Highlights of the software are provided, including benefits to the analyst. The analysis of important method validation characteristics such as linearity, accuracy, and precision is automated. These characteristics and their acceptance criteria can be captured in a method template, which adheres to the company's standard operating procedure. This template method can then be used repeatedly by other scientists in the organization, hence, eliminating the need to create a new experimental plan each time a new validation is conducted.
