November 2023

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The Evolution of LC Troubleshooting: Strategies for Improving Peak Tailing

Dwight R. Stoll
November 1st 2023
EventsColumn: LC Troubleshooting

Troubleshooting continues to evolve constantly, changing how we overcome issues such as chemical causes of peak tailing.

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Molecular Spectroscopy: Underutilized Detection for Gas Chromatography

Nicholas H. Snow
November 1st 2023
EventsColumn: GC Connections

Gas chromatography can be used in combination with molecular spectroscopy to provide structural and quantitative information on a variety of sample types.

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Current Good Manufacturing Practice (cGMP): An Overview for the Analytical Chemist

Leon Doneski;Michael W. Dong
November 1st 2023
EventsColumn: Perspectives in Modern HPLC

We provide a high-level overview of Current Good Manufacturing Practice (cGMP) regulations and their impact on the analytical chemist in the pharmaceutical industry.

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Characterization of Adeno-Associated Virus (AAV) Gene Therapy Products

Anurag S. Rathore;Jared Auclair;Anantdeep Kaur
November 1st 2023
EventsColumn: Focus on Biopharmaceutical Analysis

We present formulation and delivery of gene therapy products, focusing on adeno-associated virus (AAV) formulations. We also discuss the analytical technologies most used to characterize these products.

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Simultaneous Determination of 17 Residual Monomers in Adhesives by Gas Chromatography–Mass Spectrometry

Minxia Pan;Lanlan Zhang;Xiaoqin Liu;Dongling Liu;Yumei Qin;Honglian Yan
November 1st 2023
EventsPeer Reviewed Articles

Adhesives often contain toxic materials like residual monomers; here, we demonstrate quantitative analysis of residual monomers in adhesives using GC–MS.