LCGC Europe-12-01-2020

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The Determination of Trace Per- and Polyfluoroalkyl Substances and Their Precursors Migrated into Food Simulants from Food Contact Materials by Liquid Chromatography–MS/MS and Gas Chromatography–MS/MS

The Determination of Trace Per- and Polyfluoroalkyl Substances and Their Precursors Migrated into Food Simulants from Food Contact Materials by Liquid Chromatography–MS/MS and Gas Chromatography–MS/MS

Dan Li;Zi-hao Zhang;Huai-ning Zhong;Lei Zhu;Jing-jing Pan;Jian-guo Zheng;Qin-bao Lin;Hui Liu
December 1st 2020
ArticlePeer Reviewed

An increasing range of per- and polyfluoroalkyl substances (PFAS) has been found migrating from food contact material into food. This article establishes an integrated analytical approach combining HPLC–MS/MS and GC–MS/MS to detect 36 such PFAS.

Evolving Interaction Polymer Chromatography

Evolving Interaction Polymer Chromatography

Alasdair Matheson
December 1st 2020
ArticleFeatured Interview

LCGC Europe spoke to André Striegel about the role and benefits of interaction polymer chromatography (IPC) for polymer analysis.

Tips for LC Coupled with Charged Aerosol Detection

Tips for LC Coupled with Charged Aerosol Detection

Imad A. Haidar Ahmad
December 1st 2020
ArticleLC Troubleshooting

LC users that are new to charged aerosol detection (CAD) will find behaviours that are different from ultraviolet (UV) detectors. This article discusses some of the most important of these behaviours and provides tips to shorten the path to usable data.

Applying LC and LC–MS Methods to the Characterization and Analysis of rAAV

Applying LC and LC–MS Methods to the Characterization and Analysis of rAAV

Stephan Koza;Ximo Zhang;Hua Yang;Weibin Chen
December 1st 2020
ArticleColumn Watch

A look at the LC and LC–MS methods that are helping to overcome challenges in sample analysis, and how this can make adeno‑associated virus (AAV)–based gene therapy more accessible.