April 2022

In the second part of this review article, the recent progress in SFC for enantiomeric separations is evaluated. Several applications reported on the enantioselective separation of drugs and pharmaceutical compounds using chiral SFC are discussed, including pharmaceutical applications, clinical research, forensic toxicology, and environmental sciences.

The impact of extracolumn dispersion on kinetic plot curves is investigated. A web-based calculator that allows users to make their own kinetic plots with examples of how the tool can be used to troubleshoot underperforming columns and support column selection is discussed.

“GC Connections” presents the column’s annual review of new developments in the field of gas chromatography made available in 2021–2022.

This instalment reviews new HPLC and MS systems, modules, CDS, and other related software, and summarizes their significant features and user benefits.

LCGC Europe spoke to Selina Tisler and Jan H. Christensen about recent research projects focusing on nontargeted screening (NTS) approaches for important environmental monitoring applications.