Exploring Dengue Virus Infections with Metabolomics
May 6th 2016Researchers from Colorado State University have demonstrated the viability of exploratory metabolomics and HILIC–MS in identifying biomarkers associated with dengue virus (DENV) infections, such as dengue fever, dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS).
Identification of Synthetic Colorants Using HPLC–DAD and Chemometrics
May 6th 2016A team of researchers from the State Laboratory of Chemo/Biosensing and Chemometrics in China has developed a novel high performance liquid chromatography-diode array detection (HPLC–DAD) method for the identification of six synthetic colours in five beverages.
Split Injection GC: Setting the Split Ratio in Shoot-and-Dilute GC
April 20th 2016Jack Cochran’s new column “Practical GC” provides readers with practical advice and new experimental evidence for how to get the best results from their gas chromatography (GC) systems. This instalment looks at understanding and using split ratio for “shoot and dilute” GC.
Robust and Repeatable Nanoparticle Drug Delivery Characterization with FFF–MALS–DLS
April 20th 2016Nanoparticles hold enormous potential for targeted, well-controlled drug delivery. Extensive characterization of nanoscale drug-delivery vehicles is essential to ensure their efficacy and reproducibility. While various methods are available to characterize nanoparticle size, including dynamic light scattering (DLS), electron microscopy, and nanoparticle tracking analysis, field-flow fractionation–multi-angle light scattering (FFF–MALS) is one of the most versatile techniques to determine size, structure, and other properties. This article highlights a study demonstrating the benefits of FFF–MALS–DLS for the characterization of nanolipid particles.