Kenneth Berthelette

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Kenneth Berthelette works as a senior scientist in the Consumables and Lab Automation Group of Waters Corporation where he focuses on marketing support and collateral generation. Ken’s areas of expertise include reversed‑phase LC method development and troubleshooting and HILIC method development.

Articles

Future-Proofing Validated Pharmacopeia Methods: A Case Study of Improving Throughput and Decreasing Operational Cost

Kenneth Berthelette;Kim Haynes

July 10th 2023

How to modernize an older pharmaceutical monograph from an HPLC column to an UHPLC column, along with calculated time and solvent savings.

Modifying the Metal Surfaces in HPLC Systems and Columns to Prevent Analyte Adsorption and Other Deleterious Effects

Thomas H. Walter;Bonnie A. Alden;Jonathan L. Belanger;Kenneth Berthelette;Cheryl Boissel;Mathew DeLano;Lavelay Kizekai;Jennifer M. Nguyen;Stephen J. Shiner

June 1st 2022

A novel surface modification technology has been developed to reduce interactions between analytes and metal surfaces in HPLC instruments and columns. We demonstrate the impact of this technology on peak symmetry, peak area, and injection-to-injection and column-to-column reproducibility for several metal-sensitive analytes.