John Chasse

A recent journal article provided an overview of a dataset that includes 10,000 experimental retention times, derived from 30 different reversed-phase liquid chromatography (LC) methods.

Researchers from the University of British Columbia have introduced an assay developed and validated to measure steroids in human primary teeth using liquid chromatography-tandem spectrometry (LC-MS/MS).

Plasma samples from 47 patients with stages 1– 4 chronic kidney disease were analyzed with liquid chromatography-mass spectrometry to identify early biomarkers of the disease’s progression through metabolic pathway analysis.

A multi-faceted approach consisting of targeted quantitation, chemical profiling, and suspect screening via ultra-high performance liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS) determined the environmental and health risks stemming from crumb rubber recycled from end-of-life tires and repurposed for a variety of uses, including artificial turf fields.

A recent study of 56 Italian ciders utilizing comprehensive two-dimensional gas chromatography coupled to time-of-flight-mass spectrometry (GC×GC–TOF-MS) detected the presence of approximately 130 semi-volatile organic compounds.

In a new study, researchers explored the dynamics of immune gene expression, ruminal metabolome, and gut microbiota in cows.

Using nanoflow liquid chromatography electrospray ionization in tandem with mass spectrometry (LC-ESI-MS), researchers were able to assess baleen whale blubber and proteins extracted from that blubber.

The Agricultural Biotechnology Research Institute of Iran (Tabriz, Iran) recently utilized gas chromatography-mass spectrometry (GC-MS) to explore the impact of different animal sources and regions in Iran on the metabolome profiles of traditional yogurts.

A recent study used liquid chromatography tandem-mass spectrometry (LC-MS/MS) for a targeted proteomics analysis to establish cerebrospinal fluid-based proteomic panels for accurate primary central nervous system lymphoma diagnosis and differentiation.

A recent report from Frost & Sullivan predicts that the expanding use of chromatography in pharmaceuticals, especially in drug development and clinical research, coupled with the food and beverage industry’s heavy reliance on chromatography for quality control, is expected to accelerate market expansion to $6.60 billion in 2028.

A rapid, accurate, and quantitative method for the analysis of glucosinolates (GSLs) has been achieved through the combining of column-free liquid chromatography (LC) with direct-infusion mass spectrometry (DIMS).

Recent research utilizing tandem mass spectrometry has yielded a complete set of expressed globulin genes, which code for the main storage protein in oats as well as their chromosomal positions.

Researchers at the Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation have developed a high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method for the precise detection of dimetridazole (DMZ) and its metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI).

In this “Equipment Roundup,” the editors of LCGC International feature new instruments from Thermo Fisher and Waters, and news from Knauer regarding the environmental impact of their best-selling HPLC systems, as recently assessed by My Green Lab.

In a new study, researchers analyzed serum proteomics of advanced adenoma (AA) and colorectal cancer (CRC) using liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) and data independent acquisition methods, screening for a variety of differentially expressed proteins.

LCGC International spoke to Silvia Valverde and Ana María Ares of the University of Valladolid about their research focusing on determining nine plasticizers in honey samples by gas chromatography–mass spectrometry (GC–MS).

Research by Himanshi Upadhyaya & John V. Goodpaster of the Department of Chemistry and Chemical Biology, Indiana University Indianapolis has focused on using an odor-permeable membrane device (OPMD) to determine any changes in the odor of dynamite and have utilized gas chromatography–mass spectrometry in negative chemical ionization mode in all analysis.

Researchers at the University of Wolverhampton have utilized gas chromatography-mass spectrometry (GC-MS) in their efforts to create new scent enrichments in their efforts to trigger mating behaviors of zoo-housed lemur species.

Researchers at the Cleveland Clinic, using liquid chromatography tandem mass spectrometry (LC-MS/MS), determined that xylitol may be a risk factor related to a major adverse cardiovascular event.

Researchers have evaluated the possibility of analyzing finger sweat through liquid chromatography-mass spectrometry (LC-MS) to ensure medication adherence and as a semi-quantitative tool in therapeutic drug management assessment and report positive results.

Kevin A. Schug of The University of Texas at Arlington and his team partnered with The Lummus Technology (Pasadena, TX) to develop a method of pyrolysis based on supercritical fluid chromatography (SFC) with ultraviolet (UV) detection. Schug spoke to us about the process and the paper that resulted from its development.

The NASA Perseverance Mars Rover and its spectrometer is once again fully functional after six months of not being operational.

In this “Equipment Roundup,” the editors of LCGC International feature new instruments from Sartorius and Shimadzu.

Researchers in Western Australia have used high-performance thin layer chromatography (HPTLC) to authenticate Jarrah flower nectar and honey.

Research published in Frontiers in Environmental Science, utilizing high-resolution mass spectrometry, reports that chemical substances from tire wear have found their way into the food chain.

In this equipment roundup, the editors of LCGC International highlight new instruments from Bruker and Shimadzu.

Maria Concheiro of John Jay College (New York City) spoke to LCGC International about her research identifying and quantifying pharmaceuticals and drugs of abuse in river water samples collected from the Hudson and East Rivers in New York City, as well as investigating the possible source of these micropollutants

The global chromatography food testing market is estimated to exhibit a compound annual growth rate (CAGR) of 6.27% during the forecast period of 2023-2031, states a recent market assessment report on the subject.

Davy Guillarme of the Institute of Pharmaceutical Sciences of Western Switzerland and the School of Pharmaceutical Sciences at the University of Geneva (Switzerland) recently spoke with LCGC International about his work analyzing therapeutic oligonucleotides.

A recent study published investigates the chemoselective behavior and the interplay between enantiorecognition of organophosphorus pesticides and their metabolites under multimodal elution using liquid chromatography (LC).