Jerome Workman, Jr. serves on the Editorial Advisory Board of Spectroscopy and is the Executive Editor for LCGC and Spectroscopy. He is the co-host of the Analytically Speaking podcast and has published multiple reference text volumes, including the three-volume Academic Press Handbook of Organic Compounds, the five-volume The Concise Handbook of Analytical Spectroscopy, the 2nd edition of Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy, the 2nd edition of Chemometrics in Spectroscopy, and the 4th edition of The Handbook of Near-Infrared Analysis. Direct correspondence to: jworkman@mjhlifesciences.com
New Mass Spectrometry Measurement Tools for Characterizing Individual Cells
September 9th 2019New developments in measurement science are providing chemical information on single cells. Single-cell chemical assays provide unique information on cell heterogeneity and allow detailed studies of the metabolome and proteome for both snapshot and time-resolved studies. Recent papers describe multimodal chemical imaging, single-cell MALDI-MS supervised by immunocytochemical classification, integrating mass spectrometry with microphysiological systems for improved neurochemical studies, high throughput approaches, and others. This interview with Jonathan Sweedler explores the latest developments in mass spectrometry and separations for single cell analysis.