Aaron Acevedo is the Assistant Editor for LCGC and Spectroscopy. Direct correspondence to: aacevedo@mjhlifesciences.com
Separating Impurities from Oligonucleotides Using Supercritical Fluid Chromatography
February 21st 2025Supercritical fluid chromatography (SFC) has been optimized for the analysis of 5-, 10-, 15-, and 18-mer oligonucleotides (ONs) and evaluated for its effectiveness in separating impurities from ONs.
Assessing Thorium-Peptide Interactions Using Hydrophilic Interaction Liquid Chromatography
February 4th 2025Paris-Saclay University scientists used hydrophilic interaction liquid chromatography (HILIC) coupled to electrospray ionization mass spectrometry (ESI-MS) and inductively coupled plasma mass spectrometry (ICP-MS) to assess thorium’s interaction with peptides.