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Running a Commercial ISO 17025 POPs Lab During a Pandemic
Increasing Sensitivity by Scaling Down from Micro to Nano Flow LC
In this technical note we explore column miniaturization effects attained by reducing column ID from 300 μm to 75 μm and its effects on sensitivity.
Improved Peptide Identifications in HeLa Cell Lysates Using Core-Shell Technology
Impact of sub-2 μm fully porous particles and core-shell particles in nano LC–MS evaluated by separation performance and protein and peptide identifications in proteomics.
Deep Proteome Coverage on HeLa Lysate using a bioZen™ Fractionation Column for High pH (Basic Reversed Phase) Fractionation in Combination with a bioZen Nano Peptide XB-C18 Column for Nano Flow LC–MS
How to achieve deep proteome coverage on HeLa cell lysate using a high pH reversed phase fractionation strategy in combination with nano flow LC–MS
Determining Trap Loadability using the bioZen™ 3 μm Polar C18 Nano Column in Conjunction with the bioZen RP1 Nano Trap Column
In this application note we explore the effects of trap loadability using a bioZen 3 μm Polar C18 nano column in conjunction with the bioZen RP1 (C18) nano trap column.
Protein and Peptide Identifications for the bioZen™ Nano 2.6 μm XB-C18 LC Column in HeLa Lysate
In this technical note we show peptides and proteins identified using the bioZen nano XB-C18 column in either direct inject or trap and elute mode.
Investigating the Influence of Selectivity in Bottom Up Proteomics
The effect of column selectivity and its importance in the quality of data achieved in protein and peptide identifications in bottom-up proteomics applications is demonstrated.
Column Reproducibility and Robustness using the bioZen Nano 2.6 μm XB-C18 LC Column
In this application, we show reproducible results across multiple columns as well as the robust ability of the bioZen 2.6 μm XB-C18 column after 100 injections.
Coupling Miniaturized SPE with bioZen XB-C18 Nano Core-Shell Technology for the Detection of Sas-CoV-2 Nucelocapsid Protein Viral Peptides in Nasopharyngeal Samples
A miniaturized LC–MS and SPE method for the reliable and accurate detection of viral pesticides at 1 fmol/uL using SARS-CoV-2 nucleocapsid protein as a model system.
A New Rapid, Simple and Efficient Extraction Method for PFAS from Soils
Data Integrity: Solutions for Regulatory Compliance within a Pharma QC Environment
Solutions for Environmental Testing
Microwave Extraction of Semi-Volatile Organic Compounds from Soil
Environmental Extractions - Comparison of US EPA 3545A and 3546 Methods
The Extraction of PFAS Molecules from Spiked Soils
Automated Extraction of Semi-Volatile Organic Compounds from Soil
Hexavalent Chromium Determination Hamilton PRP-X100 Anion Exchange HPLC Column v2
Arsenic Speciation on Hamilton PRP-X100 v2
Separation of Halo Acetic Acids by Ion Exclusion
Flexible Anion Analysis with Hamilton PRP-X100 and X110 Columns v2
Separation of Aflatoxins on HxSil C18 v2
Promoter or Polluter? Separation of Triazines on HxSil C18 Column v2
Application Note: Unlock the spice
LC–HRMS Analysis of Antisense Oligonucleotide Mipomersen
Mipomersen (Kynamro®) is used as a model for the analysis of antisense oligonucleotides (ASOs) using LC-HRMS. The YMC-Triart C8 metal-free column used is an excellent choice for oligonucleotides.
Evaluation of hydrogen as a carrier gas in the analysis of residual solvents in pharmaceuticals by HS-GC-MS Introduction
Using Multidetector Asymmetric-Flow Field-Flow Fractionation To Measure Physical Properties of Liposomes and LNPs for RNA Delivery
Analysis of Drugs in Doping Control (EU)
This application note demonstrates the use of supercritical fluid chromatography (SFC) to separate highly polar and even ionic compounds.
Analysis of Drugs in Doping Control (NA)
Application Note: Characterization of AAV Attributes
This application note reviews how multi-angle and dynamic light scattering provide accurate, precise measurements of the biophysical attributes of AAV gene vectors.
Application Note: Characterization of hyperbranched hetero-polysaccharides
Learn how SEC coupled to multi-angle light scattering and viscometric detectors determines absolute molar mass, size and conformation of highly complex biopolymers.
