Vol 20 No 6 The Column June 2024 North America PDF

LCGC International spoke to Michelle Klein from the Faculty of Chemistry of the University of Duisburg-Essen (Essen, Germany) about how, by using the green analytical chemistry tool Analytical GREEnness (AGREE) and the white analytical chemistry (WAC) framework, her team was able to conduct a comparative analysis of gas chromatography-tandem mass spectrometry (GC–MS/MS), liquid chromatography-tandem mass spectrometry (LC–MS/MS), and the yeast-cell-based reporter gene assay (A-YES).

Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.

Here is some of the most popular content posted on LCGC International this week.

Agilent Technologies recognized Professor Anders Bentien of Aarhus University, Professor Walter Gössler of the University of Graz, and Professor Gregory Offer of Imperial College London as their 2025 Solutions Innovation Research Award (SIRA) recipients.

The 43rd Annual Healthcare J.P. Morgan Healthcare Conference kicked off in San Francisco earlier this week. Here’s what top executives from Agilent, Bruker, and Waters, discussed during the event.