U-GPC? Making GPC/SEC Faster
Can a UHPLC approach be easily transferred to speed up GPC/SEC measurements? Unfortunately, the answer is: No! But there are other solutions to make GPC/SEC faster
Ultra-HPLC (UHPLC) provides a new potential for method development and analysis. It is achieved by using a sub-2 µm particle size column packing at increased linear velocities. The advantage of UHPLC over conventional HPLC is the reduced analysis time without sacrificing efficiency. In comparison to traditional HPLC, analysis time can be decreased up to a factor of 7–10.
So the question for GPC/SEC users is: Can this approach be easily transferred to speed up GPC/SEC measurements? Unfortunately, the answer is: No - the UHPLC approach does not work! But there are other solutions to make GPC/SEC faster!
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Katelynn Perrault Uptmor Receives the 2025 LCGC Emerging Leader in Chromatography Award
Published: November 13th 2024 | Updated: November 13th 2024November 13, 2024 – LCGC International magazine has named Katelynn A. Perrault Uptmor, Assistant Professor of Chemistry at the College of William & Mary, the recipient of the 2025 Emerging Leader in Chromatography Award. This accolade, which highlights exceptional achievements by early-career scientists, celebrates Perrault Uptmor’s pioneering work in chromatography, particularly in the fields of forensic science, odor analysis, and complex volatile organic compounds (VOCs) research.
