The Story of Thin-Layer Chromatography

A joint study between the University of Oklahoma Health Sciences Center (Oklahoma City, Oklahoma) and the UC Davis West Coast Metabolomics Center (Davis, California) identified differentially regulated lipids in type 2 diabetes (T2D) and obesity through the application of reversed-phase liquid chromatography-accurate mass tandem mass spectrometry (RP-LC-accurate MS/MS).

Many multi-column gas chromatography systems use two-position multi-port switching valves, which can suffer from delays in valve switching. Shimadzu researchers aimed to create a new sampling and switching module for these systems.

Saba Aslani from the University of Texas at Arlington spoke to LCGC International about a collaborative project with Northwestern University, the University of Hong Kong, and BioTools, Inc., investigating mirror-image cyclodextrins using ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) and vibrational circular dichroism (VCD).

As the push for green chemistry continues to grow, University of Almeria researchers created a review for ways chromatographic techniques could be more environmentally friendly.