Researchers from Universidad Complutense de Madrid (Madrid, Spain) and Universität Dortmund (Dortmund, Germany) used a molecularly imprinted polymer (MIP) solid-phase extraction method in the analysis of fluoroquinolone antibiotics in environmental water samples.
Researchers from Universidad Complutense de Madrid (Madrid, Spain) and Universität Dortmund (Dortmund, Germany) used a molecularly imprinted polymer (MIP) solid-phase extraction method in the analysis of fluoroquinolone antibiotics in environmental water samples. The MIP was prepared using enrofloxacin as the template and a stoichiometric quantity of urea-based functional monomer to target the oxyanionic moeities in the template molecule. They characterized the polymer using nitrogen adsorption–desorption isotherms and scanning electron microscopy.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.