SPME-GC-MS Analysis of Cigarette Smoke
A researcher from Shagrao Normal University (Shangrao, Jiangxi Province, China) used solid-phase microextraction (SPME) followed by gas chromatography?mass spectrometry (GC?MS) to analyze volatile organic compounds (VOCs) in cigarette smoke.
A researcher from Shagrao Normal University (Shangrao, Jiangxi Province, China) used solid-phase microextraction (SPME) followed by gas chromatography–mass spectrometry (GC–MS) to analyze volatile organic compounds (VOCs) in cigarette smoke. The researcher used a home-made smoking machine to produce the smoke. Various SPME fibers and desorption conditions were studied. The study found that the best fiber was coated with divinylbenzene–carboxen–polydimethylsiloxane and that a desorption temperature–time of 250 °C for 3 min was optimal. The method identified 70 VOCs and provided a precision of 2–11%.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
