SPME Analysis of Aldehydes in Aqueous Solution
Chemists from the University of North Dakota (Grand Forks, North Dakota) used solid-phase microextraction (SPME) to extract aldehydes from an aqueous solution.
Chemists from the University of North Dakota (Grand Forks, North Dakota) used solid-phase microextraction (SPME) to extract aldehydes from an aqueous solution. They evaluated several SPME techniques, including headspace extraction, liquid-phase extraction, and on-fiber derivatization. The liquid-phase SPME method was the optimal method, achieving limits of detection in the 0.1–4.4 µg/L for most of the analytes. Headspace SPME with an on-fiber derivatization was less sensitive and was unable to detect several compounds.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
