Spanish Chemists Validate KDP
KDP (long-chain dipalmitate exter of kojic acid) was recently introduced to resolve skin pigment issues resulting from age spots.
KDP (long-chain dipalmitate exter of kojic acid) was recently introduced to resolve skin pigment issues resulting from age spots. As a skin-whitening agent, KDP should be controlled, to ensure efficacy and safety. As none existed, Alberto Chisvert and colleagues from the universities of Valencia and Alicante in Spain investigated set out to use size exclusion chromatography (SEC) with UV-visible detection. Sample preparation of five samples comprised ultrasonic extraction with tetrahydrofuran (THF) and dilution to the same volume for each sample. Water was avoided because it brought about precipitation of KDP. The extract was analyzed with a SEC column of polystyrene-divinylbenzene copolymer, using THF as mobile phase. KDP levels in the commercial samples were in the range 0.34-2.14% (w/w). The researchers concluded that the speed and accuracy of the SEC method for measuring KDP in skin whiteners make it a good candidate method for quality control in the cosmetics industry.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
