Sonication-Assisted Extraction of Parabens in Environmental Samples
Scientists from INIA (Madrid, Spain) used ultrasonic-assisted extraction followed by liquid chromatography with triple-quadrupole mass spectrometry detection (LC?MS) to analyze paraben compounds in environmental solid samples.
Scientists from INIA (Madrid, Spain) used ultrasonic-assisted extraction followed by liquid chromatography with triple-quadrupole mass spectrometry detection (LC–MS) to analyze paraben compounds in environmental solid samples. The sonication was performed in small glass columns. The samples were subjected to two consecutive 15-min sonication steps with acetonitrile as the extraction solvent. The sample extracts were evaporated under nitrogen and were subsequently analyzed by LC–MS. The technique was found to be suitable for analyzing methyl, ethyl, isopropyl, propyl, benzyl, and butylparaben in solid samples such as soil and sediments at trace levels.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
