Sol-Gel Coatings for SPME
A group of researchers from Universita degli Studi di Parma (Parma, Italy) developed sol-gel?synthesized coatings for solid-phase microextraction (SPME) fibers for analyzing trace-level polycyclic aromatic hydrocarbons in water.
A group of researchers from Universita degli Studi di Parma (Parma, Italy) developed sol-gel-synthesized coatings for solid-phase microextraction (SPME) fibers for analyzing trace-level polycyclic aromatic hydrocarbons in water. The researchers measured the fibers' film thickness, porosity, thermal stability, and pH resistance. A diethoxydiphenylsilane-based coating was found to provide thermal stability to temperatures as high as 400 C. Limits of detection were better than those obtained using a polydimethylsiloxane fiber.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
