News from the Chromatography industry.
Bruker Daltonics obtains Russian Medical Device Registration
Bruker Daltonics Inc. (Billerica, Massachusetts) announced that it has obtained registration of its MALDI-TOF product line of microflex, autoflex TOF or TOF/TOF, and ultraflex TOF/TOF mass spectrometers as medical devices from the Ministry of Health and Social Development of the Russian Federation.
MALDI-TOF mass spectrometry is increasingly being applied as a clinical research tool in biomarker discovery, clinical proteomics, functional genomics, molecular imaging, and microorganism identification. Bruker Daltonics now has registered its flex series MALDI-TOF mass spectrometers as medical devices in the Russian Federation, to facilitate upcoming regulatory approvals of novel mass-spectrometry based upon in vitro diagnostic assays by its Russian customers.
Eksigent appoints new CEO
Eksigent Technologies, LLC (Dublin, California) announced that David Weber has joined the company as CEO, president, and director.
Weber joins the company from Stratagene Corporation (San Diego, California), where he was vice-president of Global Marketing and Business Development.
Weber brings 30 years experience in the life science and biotechnology industries, with sales and marketing positions at companies ranging in size from start-up to over $300 million in annual sales.
PerkinElmer acquires Spectral Genomics
PerkinElmer, Inc. (Shelton, Connecticut) announced the acquisition of Spectral Genomics, Inc. (Houston, Texas), a leading company in molecular karyotyping technology used to evaluate chromosomal abnormalities.
Spectral Genomics' array products and analysis software help pharmaceutical, biotechnology, cytogenetic, and clinical researchers identify chromosomal abnormalities related to the study of cancer and pre- and post-natal genetic disorders. The company's proprietary Array CGH provides high-resolution global views of the human genome, enabling researchers to identify the exact location of any chromosomal deletions and amplifications that can cause an increased risk of genetic disease.
Thermo acquires Fisher Scientific
Thermo Electron (Waltham, Massachusetts) announced the acquisition of Fisher Scientific International Inc. (Pittsburgh, Pennsylvania).
"The combined 'Thermo Fisher Scientific,' which sees more than $9 billion in 2007 revenue, will have a 7500-member sales force. Meanwhile, the lab supply industry at large, worth an estimated $20 billion to $25 billion in annual sales, remains largely 'fragmented' with pharmaceutical and biotechnology customers demanding more one-stop shopping," said John Sullivan, an analyst with Leerink Swan & Co.
LLC-HRMS Technology Used to Track Chemical Migration in Reusable Plastic Bottles
November 18th 2024Aiming to develop a comprehensive strategy for evaluating the chemical migration from various reusable plastic bottles, researchers from the University of Copenhagen utilized vacuum evaporation concentration (VEC) enrichment combined with liquid chromatography (LC) high resolution mass spectrometry (HRMS) analysis to investigate a wide range of materials from different manufacturers to identify those with higher and lower chemical migration rates.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
RP-HPLC Analysis of Polyphenols and Antioxidants in Dark Chocolate
November 13th 2024A recent study set out to assess the significance of geographical and varietal factors in the content of alkaloids, phenolic compounds, and the antioxidant capacity of chocolate samples. Filtered extracts were analyzed by reversed-phase high-performance liquid chromatography (RP-HPLC) with ultraviolet (UV) and spectrophotometric methods to determine individual phenolics and overall indexes of antioxidant and flavonoid content.