PAHs in Tobacco Smoke
Scientists from Lorillard Tobacco Company (Greensboro, North Carolina) developed an improved method for analyzing polycyclic aromatic hydrocarbons (PAHs) in mainstream tobacco smoke.
Scientists from Lorillard Tobacco Company (Greensboro, North Carolina) developed an improved method for analyzing polycyclic aromatic hydrocarbons (PAHs) in mainstream tobacco smoke. They used two types of solid-phase extraction (SPE) media to remove matrix interferences and performed the analysis with gas chromatography–mass spectrometry (GC–MS). They achieved a reduction in analysis run time as well as an increase in accuracy. The researchers also used a chilled impinger to trap semivolatile PAHs.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
