NuGEN and Hamilton Create Automated Sample Preparation Instrument
NuGEN (San Carlos, California) and the Hamilton Company (Reno, Nevada) have assembled an automated, total target preparation system for high-throughput processing of clinical samples for global gene expression analysis.
NuGEN (San Carlos, California) and the Hamilton Company (Reno, Nevada) have assembled an automated, total target preparation system for high-throughput processing of clinical samples for global gene expression analysis. The system, which consists of NuGEN’s Ovation Systems RNA amplification and labeling products and Hamilton’s Microlab Starlet benchtop liquid handling system, was engineered to increase throughput and improve workflow for small RNA samples used in clinical signature and biomarker discovery.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
