Nanomedicine, well-characterized – how FFF-MALS provides detailed and quantitative analysis of size, structure, concentration and encapsulation

A new study, published by a researcher from Chemical Characterization Solutions in Minnesota, explored a new approach for sample preparation for the chemical characterization of medical devices.

A team of scientists from the Paris university developed and optimized MAVERIC, a miniaturized and autonomous gas chromatography (GC) system coupled to a nano-gravimetric detector (NGD) based on a NEMS (nano-electromechanical-system) resonator.

University of Valladolid scientists used a miniaturized method for analyzing biogenic volatile organic compounds (BVOCs) emitted by tree species, using headspace solid-phase microextraction coupled with gas chromatography and quadrupole time-of-flight mass spectrometry (HS-SPME-GC–QTOF-MS) has been developed.

Analytical scientists are faced with the task of finding the right column from an almost unmanageable range of products. This paper focuses on columns that enable protein analysis under native conditions through size exclusion, hydrophobic interaction, and ion exchange chromatography. It will highlight the different column characteristics—pore size, particle size, base matrices, column dimensions, ligands—and which questions will help decide which columns to use.