Molecularly Imprinted SPME in Analysis of Beta Blockers
Researchers from Sun Yat-sen University and South China Normal University (both in Guangzhou, China) developed a sample preparation method for extracting the beta-blockers propranolol, atenolol, pindolol, and alprenolol from human plasma and urine samples.
Researchers from Sun Yat-sen University and South China Normal University (both in Guangzhou, China) developed a sample preparation method for extracting the beta-blockers propranolol, atenolol, pindolol, and alprenolol from human plasma and urine samples. The method involved preparing a molecularly imprinted polymer (MIP)–coated solid-phase microextraction (SPME) fiber with propranolol as a template. The MIP coating had an average thickness of 25 µm and was highly crosslinked and porous. The MIP-coated fiber provided specific selectivity for the beta-blockers compared with only nonspecific adsorption achieved using non-imprinted polymer fibers. They linked the SPME method with high performance liquid chromatography for a quantitative analysis.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
