Molecularly Imprinted Polymer SPE of Quinolones
Researchers from Hebei University and Baoding University (both in Baoding, China) used water-compatible molecularly imprinted polymers as a sorbent for solid-phase extraction (SPE) of nine quinolones from urine samples.
Researchers from Hebei University and Baoding University (both in Baoding, China) used water-compatible molecularly imprinted polymers as a sorbent for solid-phase extraction (SPE) of nine quinolones from urine samples. They used UV and IR spectroscopy and proton nuclear magnetic resonance spectroscopy to investigate the sorbent’s molecular recognition mechanisms. The sorbent was able to extract the analytes selectively and simultaneously eliminate matrix interferences. Detection limits for the method reportedly were in the 0.036–0.10 µg/mL range.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
