Michael W. Dong Joins LCGC's Edtorial Advisory Board
LCGC Magazine is pleased to announce the addition of Michael W. Dong, PhD, to its editorial advisory board.
LCGC
Magazine is pleased to announce the addition of Michael W. Dong, PhD, to its editorial advisory board.
Dong is a senior scientist in the Small Molecule Drug Discovery group at Genentech (South San Francisco, CA), a position he has held since 2007. He formerly served as a research director at Synomics Pharma (Wareham, MA), a research fellow at Purdue Pharma (Cranbury, NJ), a senior staff scientist at Applied Biosystems/PerkinElmer (Foster City, CA), and a section head in Hoechst Celanese (Bridgewater, NJ).
Don has conducted training courses at national meetings (ACS, Pittcon, EAS AAPS, HPLC) on High Performance Liquid Chromatography (HPLC) in pharmaceutical analysis and Drug Metabolism and Pharmacokinetics, HPLC method development, ultra high-pressure LC, the drug development process for scientists, and drug quality. His publishing credentials include more than 80 publications in chromatography and analytical chemistry. He has authored a bestseller in chromatography, Modern HPLC for Practicing Scientists (Wiley, 2006) and co-edited Handbook of Pharmaceutical Analysis by HPLC (Elsevier/Academic Press, 2005).
Dong received his doctorate in analytical chemistry from the City University of New York, and a certificate in biotechnology from the University of California, Santa Cruz.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
2024 EAS Awardees Showcase Innovative Research in Analytical Science
November 20th 2024Scientists from the Massachusetts Institute of Technology, the University of Washington, and other leading institutions took the stage at the Eastern Analytical Symposium to accept awards and share insights into their research.
