Meeting UHPLC Needs with High Purity Water
In recent years the advent of ultra high performance liquid chromatography (UHPLC) has broadened the scope of laboratory applications, making it possible to attain extremely low detection limits.
In recent years the advent of ultra high performance liquid chromatography (UHPLC) has broadened the scope of laboratory applications, making it possible to attain extremely low detection limits. However, there are certain requirements when working with this sensitive analytical technique:high purity water, solvents and reagents are necessary to take full advantage of UHPLC and achieve representative analytical data. Here a series of experiments demonstrates that freshly produced ultrapure water is suitable for UHPLC.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
