Introducing Atlanta...
An introduction to the city that hosts Pittcon in 2011 with some of the places of interest that are not to be missed.
To the history buffs in The Column’s readership, the fact that Atlanta derives its name from the Lost City of Atlantis may be common knowledge (and has no doubt helped win many games of Trivial Pursuit). However, did you know that the original name of the City of Atlanta was the more mundane and improbable “Terminus,” based on the fact that it sprouted up at the end of an old rail line? This piece of trivia is one of the surprises with regard to the city of Atlanta amongst a host of others that bode well for the annual Pittcon Conference, set to take place at the Georgia World Congress Center between 13–18 March 2011.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Measuring Vitamin D3 in Hen's Egg Yolk with HPLC
January 29th 2025Researchers have developed a method employing high performance liquid chromatography with ultraviolet detection (HPLC-UV) to determine vitamin D3 in food (even in the presence of vitamin D2, and with a specific focus on egg yolk) in a cost-effective and quantitative manner.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
