A wide range of instruments, columns and media are available for LC purification, including Flash and HPLC. Are these techniques interchangeable? How do they compare?
A wide range of instruments, columns and media are available for LC purification, including Flash and HPLC. Are these techniques interchangeable? How do they compare? In our experience sample complexity and solubility, and economics are the main factors determining the choice of technique.
Polysorbate Quantification and Degradation Analysis via LC and Charged Aerosol Detection
April 9th 2025Scientists from ThermoFisher Scientific published a review article in the Journal of Chromatography A that provided an overview of HPLC analysis using charged aerosol detection can help with polysorbate quantification.
Removing Double-Stranded RNA Impurities Using Chromatography
April 8th 2025Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how chromatography can be used to remove double-stranded RNA impurities during mRNA therapeutics production.