The authors developed an analytical method for the fast analysis of vitamins in a complex matrix using in-line and complementary high performance liquid chromatography with photodiode-array and mass spectrometry detection techniques. The method development was significantly faster when the authors used both the UV-vis spectral scanning capability of a photodiode-array detector and the mass spectral scanning capability of an ion-trap mass spectrometer.
LCGC 17(9), 854–864 (1999).Polysorbate Quantification and Degradation Analysis via LC and Charged Aerosol Detection
April 9th 2025Scientists from ThermoFisher Scientific published a review article in the Journal of Chromatography A that provided an overview of HPLC analysis using charged aerosol detection can help with polysorbate quantification.
Removing Double-Stranded RNA Impurities Using Chromatography
April 8th 2025Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how chromatography can be used to remove double-stranded RNA impurities during mRNA therapeutics production.