E-Separation Solutions
There is an old saying regarding the world of fashion that says if you wait long enough, everything comes back into style eventually.
There is an old saying regarding the world of fashion that says if you wait long enough, everything comes back into style eventually. While this saying may have provided the necessary excuse for many people (myself included) to avoid throwing away favorite old articles of clothing, the underlying truth that everything is cyclical cannot be denied, and this certainly holds just as true for the field of chromatography as it does for any other field.
Earlier in the year, the stock market was at its lowest point in over ten years, and many feared the recession might even deepen into a depression. At the same time, the acetonitrile shortage was at its peak, with many laboratories feeling the crunch of this unexpected rise in the cost of solvent. Things looked grim, and the outlook was dark to say the least.
Now, just a few months later, that cycle has begun to shift and the wheels have begun turning in the right direction, albeit at a slow pace. The stock market, while nowhere near its highs from just a couple of years ago, has recovered at least some of its losses. And the supply of acetonitrile is slowly coming back as well, although all indications are that, like oil, the price may never return to the previous levels that many had become accustomed to.
Only time will tell if the cycle continues turning in this direction, but for now, it is safe to say that the outlook for the chromatography industry is discernibly brighter than it was when the year began. And as always, you can rely on LCGC to bring you the most reliable information on these issues and more, from the most respected and knowledgeable sources in the industry today — experts like Ron Majors, who addresses the ACN shortage and continued price spike in a special addendum to his column this month. This is a must-read for any reader whose daily work involves the use of this solvent.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
2024 EAS Awardees Showcase Innovative Research in Analytical Science
November 20th 2024Scientists from the Massachusetts Institute of Technology, the University of Washington, and other leading institutions took the stage at the Eastern Analytical Symposium to accept awards and share insights into their research.