Dispersive Liquid-Liquid Microextraction GC Method
Researchers from National Tsing Hua University (Hsinchu, Taiwan) developed a dispersive liquid?liquid microextraction (DLLME) method based on solidification of a floating organic drop and combined it with gas chromatography with either electron-capture or mass spectrometry detection.
Researchers from National Tsing Hua University (Hsinchu, Taiwan) developed a dispersive liquid–liquid microextraction (DLLME) method based on solidification of a floating organic drop and combined it with gas chromatography with either electron-capture or mass spectrometry detection. The method reportedly is simple, inexpensive, and precise. It also avoids the use of high-toxicity solvents usually used in DLLME. They used halogenated organic compounds in water as the model compounds for the method.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
