Digital Update
ALMSCO International announced it has made several significant enhancements to its ClearView chromatography/MS data reprocessing software, which is distributed exclusively by Markes.
Chromatography/MS software
ALMSCO International announced it has made several significant enhancements to its ClearView chromatography/MS data reprocessing software, which is distributed exclusively by Markes. ClearView is now available on a 12-month licence in addition to the time-unlimited version. The software is now reported to be compatible with all major GC–MS vendors' data acquisition and analysis software and some LC–MS formats. ClearView uses a dynamic background compensation (DBC) algorithm to distinguish between chromatographic peaks and chromatographic background/baseline anomalies in stored data files; the original data files are left intact and unaffected. According to the companies it aids the automatic identification of trace components by eliminating noise and background interference and improves the repeatability of integration/quantification.
Replacing paper-based protocols
Waters has announced an expansion of its liquid chromatography system qualification tool for its Empower Chromatography Software. The Empower Systems Qualification Tool (SystemsQT), which has been available only for Waters instruments, now supports Agilent 1100 and 1200 series HPLC Systems in laboratories that use Waters Empower software for enterprise chromatography data management. According to the company the software tool reduces the amount of time to qualify Agilent HPLCs by 40% when compared with traditional, paper-based protocols. This tool is designed to give laboratories a means to replace currently paper-based and labour-intensive qualification/re-qualification protocols with a new standard for automated and 21 CFR Part 11 compliant qualification. The company claims that for regulated laboratories with large numbers of liquid chromatographs, the savings could be dramatic because streamlining the qualification process reduces downtime and increases instrument utilization rates.
Preparative LC software
ClarityChrom Prep is Knauer's preparative HPLC software solution, which features a graphical editor for intuitive fraction-collection programming, a graphical presentation of the fraction collector rack and linking between fraction vials and the corresponding chromatogram. According to the company it supports control of a feed pump and control for fraction collectors from B?chi, ISCO and Knauer. Peak recognition can be triggered by either "level", "slope", or "level and/or slope" separately for peak begin and peak end. Solvent recycling can be carried out within the peak recognition interval. In addition, the fraction collector can be controlled manually and switched to "collect", "waste" or "solvent recycling" position during a run. For timed events the user can define the respective vial positions. Besides this, the software is a full featured analytical HPLC software solution including Autosampler control.
Alpha MOS new website
Alpha MOS has introduced a new website including numerous features and sources of information, such as user testimonials in various industrial areas, a section dedicated to human and instrumental sensory analysis with quality and R&D application examples and hot topics on new products and applications. The information is searchable by industry, application and solution, and products and services can be viewed on-line and sorted by application. The website is available in English, French, Chinese.
2024 EAS Awardees Showcase Innovative Research in Analytical Science
November 20th 2024Scientists from the Massachusetts Institute of Technology, the University of Washington, and other leading institutions took the stage at the Eastern Analytical Symposium to accept awards and share insights into their research.
Inside the Laboratory: The Richardson Group at the University of South Carolina
November 20th 2024In this edition of “Inside the Laboratory,” Susan Richardson of the University of South Carolina discusses her laboratory’s work with using electron ionization and chemical ionization with gas chromatography–mass spectrometry (GC–MS) to detect DBPs in complex environmental matrices, and how her work advances environmental analysis.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Infographic: Be confidently audit ready, at any time and reduce failures in pharma QC testing
November 20th 2024Discover how you can simplify the audit preparation process with data integrity dashboards that provide transparency to key actions, and seamlessly track long-term trends and patterns, helping to prevent system suitability failures before they occur with waters_connect Data Intelligence software.
Critical Role of Oligonucleotides in Drug Development Highlighted at EAS Session
November 19th 2024A Monday session at the Eastern Analytical Symposium, sponsored by the Chinese American Chromatography Association, explored key challenges and solutions for achieving more sensitive oligonucleotide analysis.
