ALMSCO International announced it has made several significant enhancements to its ClearView chromatography/MS data reprocessing software, which is distributed exclusively by Markes.
ALMSCO International announced it has made several significant enhancements to its ClearView chromatography/MS data reprocessing software, which is distributed exclusively by Markes. ClearView is now available on a 12-month licence in addition to the time-unlimited version. The software is now reported to be compatible with all major GC–MS vendors' data acquisition and analysis software and some LC–MS formats. ClearView uses a dynamic background compensation (DBC) algorithm to distinguish between chromatographic peaks and chromatographic background/baseline anomalies in stored data files; the original data files are left intact and unaffected. According to the companies it aids the automatic identification of trace components by eliminating noise and background interference and improves the repeatability of integration/quantification.
Waters has announced an expansion of its liquid chromatography system qualification tool for its Empower Chromatography Software. The Empower Systems Qualification Tool (SystemsQT), which has been available only for Waters instruments, now supports Agilent 1100 and 1200 series HPLC Systems in laboratories that use Waters Empower software for enterprise chromatography data management. According to the company the software tool reduces the amount of time to qualify Agilent HPLCs by 40% when compared with traditional, paper-based protocols. This tool is designed to give laboratories a means to replace currently paper-based and labour-intensive qualification/re-qualification protocols with a new standard for automated and 21 CFR Part 11 compliant qualification. The company claims that for regulated laboratories with large numbers of liquid chromatographs, the savings could be dramatic because streamlining the qualification process reduces downtime and increases instrument utilization rates.
ClarityChrom Prep is Knauer's preparative HPLC software solution, which features a graphical editor for intuitive fraction-collection programming, a graphical presentation of the fraction collector rack and linking between fraction vials and the corresponding chromatogram. According to the company it supports control of a feed pump and control for fraction collectors from B?chi, ISCO and Knauer. Peak recognition can be triggered by either "level", "slope", or "level and/or slope" separately for peak begin and peak end. Solvent recycling can be carried out within the peak recognition interval. In addition, the fraction collector can be controlled manually and switched to "collect", "waste" or "solvent recycling" position during a run. For timed events the user can define the respective vial positions. Besides this, the software is a full featured analytical HPLC software solution including Autosampler control.
Alpha MOS has introduced a new website including numerous features and sources of information, such as user testimonials in various industrial areas, a section dedicated to human and instrumental sensory analysis with quality and R&D application examples and hot topics on new products and applications. The information is searchable by industry, application and solution, and products and services can be viewed on-line and sorted by application. The website is available in English, French, Chinese.
New Study Uses MSPE with GC–MS to Analyze PFCAs in Water
January 20th 2025Scientists from the China University of Sciences combined magnetic solid-phase extraction (MSPE) with gas chromatography–mass spectrometry (GC–MS) to analyze perfluoro carboxylic acids (PFCAs) in different water environments.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ion used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.