Collagenase-Assisted Extraction of Pharmaceutical Compounds
Researchers from Banyu Pharmaceutical Co. (Ibaraki, Japan) used a novel extraction method to prepare drugs in gelatin capsules for analysis by high performance liquid chromatography.
Researchers from Banyu Pharmaceutical Co. (Ibaraki, Japan) used a novel extraction method to prepare drugs in gelatin capsules for analysis by high performance liquid chromatography. In the method, collagenase degraded the gelatin into fragments with reduced hydrophobicity, which allowed the immediate elution of gelatin-related peaks and eliminated interference with the drug peak. Gelatin has a strong UV absorption that can overlap with drug absorbances. The method eliminates powder loss caused by opening a gelatin capsule manually.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
