Cold Fiber SPME Device
Researchers from the University of Waterloo (Waterloo, Canada) designed and constructed a cold fiber solid-phase microextraction (SPME) device and applied it to the analysis of off flavors in a rice sample.
Researchers from the University of Waterloo (Waterloo, Canada) designed and constructed a cold fiber solid-phase microextraction (SPME) device and applied it to the analysis of off flavors in a rice sample. The device was based on thermoelectric cooling via a three-stage thermoelectric cooler that cooled a copper rod coated with a poly(dimethylsiloxane) hollow fiber that served as the SPME fiber. They examined three compounds in the rice: hexanal, nonanal, and undecanal, which were identified by retention times in a gas chromatography–flame ionization detection system. The cooled fiber device reportedly resulted in better reproducibility and shorter analysis time compared with a conventional solvent extraction method.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
