Carbon Nanotubes Used as SPME Medium for Aniline Compounds
Scientists from Lanzhou University (Lanzhou, China) developed an automated on-line method for determining substituted aniline compounds that consisted of in-tube solid-phase microextraction (SPME) with oxidized multiwalled carbon nanotubes coated on the outside surface of the SPME fiber, which was inserted into PEEK tubing attached to a six-port injection valve.
Scientists from Lanzhou University (Lanzhou, China) developed an automated on-line method for determining substituted aniline compounds that consisted of in-tube solid-phase microextraction (SPME) with oxidized multiwalled carbon nanotubes coated on the outside surface of the SPME fiber, which was inserted into PEEK tubing attached to a six-port injection valve. The extraction step was followed by high performance liquid chromatography (HPLC). In the extraction procedure, a constant flow pump drove the sample solution through the PEEK tubing and the nanotubes adsorbed the analytes. The valve then was switched to allow analyte desorption and injection into the HPLC system.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
