LCGC is planning to publish the next issue of The Application Notebook special supplement in June.
LCGC is planning to publish the next issue of The Application Notebook special supplement in June. The publication will include vendor application notes that describe techniques and applications of all forms of chromatography and capillary electrophoresis that are of immediate interest to users in industry, academia, and government. If your company is interested in participating in these special supplements, contact:
Michael J. Tessalone, Group Publisher,
(732) 346-3016
Edward Fantuzzi, Associate Publisher,
(732) 346-3015
Stephanie Shaffer, East Coast Sales Manager,
(508) 481-5885
It is important that each company's material fit within the allotted space. The editors cannot be responsible for substantial editing or handling of application notes that deviate from the following guidelines:
Each application note page should be no more than 500 words in length and should follow the following format.
All text will be published in accordance with LCGC's style to maintain uniformity throughout the book. It also will be checked for grammatical accuracy, although the content will not be edited. Text should be sent in electronic format, preferably using Microsoft Word.
Refer to photographs, line drawings, and graphs in the text using arabic numerals in consecutive order (Figure 1, etc.). Company logos, line drawings, graphs, and charts must be professionally rendered and submitted as .TIF or .EPS files with a minimum resolution of 300 dpi. Lines of chromatograms must be heavy enough to remain legible after reduction. Provide peak labels and identification. Provide figure captions as part of the text, each identified by its proper number and title. If you wish to submit a figure or chromatogram, please follow the format of the sample provided below.
Figure 1
Each table should be typed as part of the main text document. Refer to tables in the text by roman numerals in consecutive order (Table I, etc.). Every table and each column within the table must have an appropriate heading. Table number and title must be placed in a continuous heading above the data presented. If you wish to submit a table, please follow the format of the sample provided below.
Table I: Factor levels used in the designs
Literature citations must be indicated by arabic numerals in parentheses. List cited references at the end in the order of their appearance. Use the following format for references:
(1) T.L. Einmann and C. Champaign, Science 387, 922–930 (1981).
Analyzing Bone Proteins in Forensic Laboratories Using LC−MS/MS
November 4th 2024A recent study compared different workflows for extracting, purifying, and analyzing bone proteins using liquid chromatography with tandem mass spectrometry (LC–MS/MS), including an in-StageTip protocol previously optimized for forensic applications, and two protocols using novel suspension-trap technology (S-Trap) and different lysis solutions. LCGC International discussed this work with Noemi Procopio of the School of Law and Policing and the Research Centre for Field Archaeology and Forensic Taphonomy at the University of Central Lancashire (UK), corresponding author of the paper that resulted from this study.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Profiling Volatile Organic Compounds in Whisky with GC×GC–MS
November 1st 2024Researchers from Austria, Greece, and Italy conducted a study to analyze volatile organic compounds (VOCs) present in Irish and Scotch whiskys using solid-phase microextraction (SPME) Arrow with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) to examine the organoleptic characteristics that influence the taste of spirits.