In response to the recent discovery of dangerous levels of dioxins in animal feed produced in Germany, Phenomenex has announced its publication of a method for analysing the chemicals using high-resolution gas chromatography with mass spectrometric detection.
In response to the recent discovery of dangerous levels of dioxins in animal feed produced in Germany, Phenomenex has announced its publication of a method for analysing the chemicals using high-resolution gas chromatography with mass spectrometric detection (HRGC–MS).
Dioxins enter the environment and subsequently the food chain through combustion of organic materials in waste incineration. Recently, fat incorporated into feed products in Germany were found to be highly contaminated, and were reported to threaten a chain-reaction through the food supply. As a result several countries banned imports of animal products from Germany as a precautionary measure.
“While dioxin contamination is generally on the decline due to aggressive regulatory action, we can still see accidents, such as the one in Germany,” explains Sky Countryman, manager of applications and applied technology for the company. “Robust analytical testing procedures are still in demand for the determination of potential dioxin threats in both feed and animal fat.”
The method, developed in collaboration with Vista Analytical, also analyses dioxin-like compounds dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs), which are often monitored in conjunction with dioxins to give an overall toxic equivalent (TEQ) for a sample. The method has also been used to analyse non-organic chicken feed as well as fish from the Mississippi River and Great Lakes and shrimp from a variety of international sources.
The technical note on the HRGC–MS method can be accessed at www.phenomenex.com/dioxin.
Analytical Challenges in Measuring Migration from Food Contact Materials
November 2nd 2015Food contact materials contain low molecular weight additives and processing aids which can migrate into foods leading to trace levels of contamination. Food safety is ensured through regulations, comprising compositional controls and migration limits, which present a significant analytical challenge to the food industry to ensure compliance and demonstrate due diligence. Of the various analytical approaches, LC-MS/MS has proved to be an essential tool in monitoring migration of target compounds into foods, and more sophisticated approaches such as LC-high resolution MS (Orbitrap) are being increasingly used for untargeted analysis to monitor non-intentionally added substances. This podcast will provide an overview to this area, illustrated with various applications showing current approaches being employed.
Detangling the Complex Web of GC×GC Method Development to Support New Users
September 12th 2024The introduction of comprehensive two-dimensional gas chromatography (GC×GC) to the sample screening toolbox has substantially increased the ability to comprehensively characterize complex mixtures. However, for many gas chromatography (GC) users, the thought of having to learn to develop methods on a new technology is daunting. Developing a basic GC×GC method for most (nonspecialized) applications can be accomplished in minimal time and effort given parameter suggestions and ranges to target analytes in a sample of interest. In this article, the authors work describe a simple workflow to develop a GC×GC method for a specific sample upon initial use, with the aim of decreasing the time to accomplish functional workflows for new users.
The Reality Behind Column Insertion Distance
September 10th 2024Column insertion distance is critical to good chromatography. What happens if the column is installed too low in the injection port? Is insertion distance more important when performing split injection or splitless injection? Does the position of the column in the injection port impact reproducibility?