Dr Ronald A. DePinho ? president of the University of Texas MD Anderson Cancer Center (Texas, USA) ? has received an Agilent Thought Leader Award.
Dr Ronald A. DePinho — president of the University of Texas MD Anderson Cancer Center (Texas, USA) — has received an Agilent Thought Leader Award. Agilent Technologies (California, USA) will provide financial support for personnel as well as instrumentation for the center.
The work of DePinho has resulted in the development of improved cancer detection methods and cancer drug development. His research group focuses broadly on basic‑to‑translational research programmes for brain, colorectal, pancreas and prostate cancers, as well as ageing and neuro‑degeneration.
The award will support DePinho and his team in their research into reprogramming the metabolome at the initial stages of cancer. Specifically, the instrumentation will “enhance” the investigation of metabolic adaptions during the development of pancreatic cancer, according to Dr Guilio Draetta, director of the Institute for Applied Cancer Science.
Pancreatic cancer is a major concern of DePinho’s group because survival rates of patients have not significantly improved over the past two decades. Depinho said: “This technology will allow us to rapidly identify new targets that drive the formation, progression and maintenance of pancreatic cancer. Discoveries from this research will also lead to the development of effective early detection biomarkers and novel therapeutic interventions.”
Patrick Kaltenbach, Agilent VP and general manager of the Liquid Phase division, said: “We are proud to support Dr DePinho’s exciting translational research programme, which will make use of metabolomics and integrated biology workflows and solutions in biomarker discovery.”
Draetta added: “Armed with novel biomarkers, earlier diagnosis and treatment will be possible, leading to improved patient outcomes. Additional opportunities for novel therapeutic intervention will also emerge from this work.”
For more information please visit:
www.agilent.com
This story originally appeared in The Column. Click here to view that issue.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.